High- and low-throughput scoring of fat mass and body fat distribution in C. elegans

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High- and low-throughput scoring of fat mass and body fat distribution in C. elegans.

Fat accumulation is a complex phenotype affected by factors such as neuroendocrine signaling, feeding, activity, and reproductive output. Accordingly, the most informative screens for genes and compounds affecting fat accumulation would be those carried out in whole living animals. Caenorhabditis elegans is a well-established and effective model organism, especially for biological processes tha...

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Background. Adolescence is a critical period of growth and different variables can effect on this process in this age period. The relationship between obesity in adolescence and some metabolic disorders in the future has been reported by many studies. This study was carried out to determine the pattern of fat distribution among high school adolescents in Ilam city in 2013. Method. In this cross...

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The nematode C. elegans has emerged as an important model for the study of conserved genetic pathways regulating fat metabolism as it relates to human obesity and its associated pathologies. Several previous methodologies developed for the visualization of C. elegans triglyceride-rich fat stores have proven to be erroneous, highlighting cellular compartments other than lipid droplets. Other met...

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pattern of fat distribution (waist to hip ratio) and body mass index in high school adolescents in ilam

background. adolescence is a critical period of growth and different variables can effect on this process in this age period. the relationship between obesity in adolescence and some metabolic disorders in the future has been reported by many studies. this study was carried out to determine the pattern of fat distribution among high school adolescents in ilam city in 2013. method. in this cross...

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ژورنال

عنوان ژورنال: Methods

سال: 2014

ISSN: 1046-2023

DOI: 10.1016/j.ymeth.2014.04.017